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6.2 Postmarketing Experience Additional adverse reactions have been identified during postapproval use

63 (14), e1900248

Concentration-dependent increases in lipid-associated ROS of neutrophils were observed with the addition of SLE IgG or IFN- in normal serum, which could be reversed by depleting IgG or antagonizing IFN- receptor

This is a theoretical concern raised by the biology, not a demonstrated harm in humans for either compound, and it should be described as exactly that an unresolved question that the absence of long-term human data leaves open, not a proven risk and not a reason for false reassurance either

But true access also requires ensuring members are using the right drug for the right reasons