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Characterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma lucidum

The concept of NVU was introduced as a structure formed by neurons, astrocytes, basal lamina covered with smooth muscle cells and pericytes, endothelial cells (components of the BBB), and extracellular matrix (Harder et al., 2002)

In neurons and mouse Parkinsons models, nicotine reduced SIRT6, a ritalin linked to heightened TNF- signaling and neuroinflammation, and this reduction contributed to neuroprotection

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