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Implementing aging effects in the model Aging is a multifactor phenomenon that affects metabolism at different levels, such as transcriptome, proteome, metabolome, and potentially even kinetic properties of enzymes and transporters owing to accumulated genetic damage, lower protein synthesis fidelity, and higher chances of protein misfolding

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For context, the first-trimester miscarriage rates are greater in some of the drug groups studied, for example, 29 percent compared to 13 percent in controls, and congenital abnormality rates differ between cohorts

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The desolvation temperature was set at 450 C, and the desolvation gas flow, collision gas flow, and nebulization gas flow were set to 1000 L/h, 0.15 min/mL, and 7.00 bar, respectively