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Serious Side Effects In rare cases, semaglutide can cause more serious side effects, like: Pancreatitis Kidney problems Gallbladder disease Thyroid tumors (observed in animal studies) Managing Side Effects Common side effects are mild and inclined to reduce over time as the body regulates according to the medication

Cortisol-driven weight gain is a common challenge for many people, especially when stress levels are high

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ED is also not reported as a common adverse effect seen with Ozempic and any other semaglutide medication 7