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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

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To mitigate potentially detrimental weight loss in the evoke/evoke+ population, the weight of participants is being monitored throughout the trials, and a flexible-dosing approach is being implemented

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However, in patients with PD, factors such as glutathione (GSH) depletion, impaired function of the Nrf2/ARE signaling pathway, and mitochondrial dysfunction contribute to a significant decrease in antioxidant levels in the substantia nigra region