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As each dataset has multiple experimental groups, to correct for the variance between studies while preserving variance between cell types and experimental groups, we trained the single-cell variational inference (scVI) model 55 on the control groups from each study with the study as the batch key, and then integrated the experimental groups (Extended Data Fig

It was derived from GHRP-1 through a systematic chemistry programme that identified active analogues lacking the central Ala-Trp dipeptide of the parent compound, ultimately yielding ipamorelin as the most pharmacologically refined member of its series

Seleno-independent glutathione peroxidases

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Homocysteine and methylation markers: The transsulfuration pathway connects methylation to glutathione synthesis, making these markers relevant to antioxidant assessment