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19 The SC identified an additional 1140 cases suggesting that they may indeed be less specific compared to the HSTC and likely picks up milder cases where off-target neurotransmitter effects contribute to a broader nonspecific toxicity presentation

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The Phase 2 retatrutide trial (PMID 37366315) reported -24.2% body weight change at the 12 mg weekly dose across 48 weeks

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