Digestion Compromised digestion can be an underlying factor, especially of autoimmune thyroid disease such as Hashimotos Thyroiditis, due to the association with increased intestinal permeability (Leaky Gut). 8 This is often mediated by gluten, 9 imbalanced gut bacteria, 10 and stress, 11 which drives autoimmunity, especially if an individual is genetically susceptible. 12 If food is also poorly digested, say from eating on the go, and moves through the gut too fast due to diarrhoea, nutrient absorption becomes harder
A key controller of this cellular defense mechanism is the Nrf2 (nuclear factor erythroid 2related factor 2)-antioxidant response element (ARE) pathway
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The association between dietary vitamin B1 intake and constipation: a population-based study
The effects of the paleo diet on autoimmune thyroid disease: A mixed methods review