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Results May Vary: Individual results differ

The trial in people with T2D included 281 participants (mean age 56 years, 56% women, mean BMI 35.0 kg/m 2 , mean HbA1c 8.3%) treated with lifestyle only and/or metformin, with similar intervention arms to the obesity trial, albeit retatrutide 0.5 mg rather than 1 mg, and dulaglutide 1.5 mg was an additional comparator [46]

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To establish the proportion of differentially expressed genes that were potentially regulated directly by GH, we compared the data by orthology with mouse genes identified as having STAT5 bound to putative regulatory elements by chromatin immunoprecipitation sequencing (ChIP:seq)

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