These include: Nausea and vomiting up to 20% of people report some nausea Diarrhea Constipation Gas and bloating Abdominal discomfort Fatigue Belching Hair loss due to rapid weight loss In rare cases, kidney, pancreas, thyroid, or gallbladder issues may arise, but these are uncommon
Celsa C, Pennisi G, Tulone A, Ciancimino G, Vaccaro M, Infantino G, et al
GLP-1 receptor agonists reduce CGRP expression, lower neuroinflammation, and decrease intracranial pressure, all of which are relevant to migraine pathophysiology
Centers for Medicare and Medicaid Services
The next-generation therapy combines semaglutide with cagrilintide, a long-acting analog of amylin, which is a pancreatic peptide that lowers blood glucose levels and slows down gastric emptying