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When to seek medical review Numbness, tingling, weakness, shortness of breath, chest pain, severe fatigue, unexplained weight loss, or neurological symptoms should be discussed with a GP or urgent service as appropriate

Y.LehouxS.et al (2019)

Safety, tolerability, and pharmacokinetics of an oral small molecule inhibitor of IL-17A (LY3509754): a phase I randomized placebo-controlled study

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Hershman randomized women receiving adjuvant taxane chemotherapy for early breast cancer evenly to either oral ALC 1,000 mg three times daily or matching placebo, for 24 weeks