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The representative SASP factors include pro-inflammatory cytokines, chemokines, and proteases, which can cause an imbalance in cartilage hemostasis, resulting in degradation or other dysfunctions (Li and Pei, 2012)
In Vitro and Cellular Systems for the Characterization of Bioactivating and Inactivating Drug Metabolizing Enzymes in Adverse Drug Reactions
People may be able to reduce the pain of injections by numbing their skin, relaxing their muscles, distracting themselves, and rotating the injection site each time
J Neurochem 71:25102517 Bogaert YE, Rosenthal RE, Fiskum G (1994) Postischemic inhibition of cerebral cortex pyruvate dehydrogenase
Rusiecki JA, Baccarelli A, Bollati V, Tarantini L, Moore LE, Bonefeld-Jorgensen EC
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