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Chang W, Zhu F, Zheng H, Zhou Z, Miao P, Zhao L, et al

Gene variants: specific NNMT variants associated with BMI and resting energy expenditure in human studies

A new study published in The Lancet Regional Health found that use of GLP-1 receptor agonists in the context of weight-loss treatment is associated with declines in lean (muscle) mass unless accompanied by targeted strength training interventions

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This makes it a critical subject of study for cases where traditional incretin therapies have reached a plateau or where hepatic steatosis is a primary concern