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Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (pioneer 9): a 52-week, phase 2/3a, randomised, controlled trial

10.3803/ENM.2015.30.2.117 41 LeeJ

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Gradual adjustments may help: reduce nausea or digestive discomfort improve medication tolerance support consistent progress allow individualized dose optimization Increasing too quickly may increase the likelihood of digestive symptoms, which is why gradual progression is commonly recommended

The purpose of this article is to answer common questions and concerns about semaglutide and Mirena