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More serious but rare safety considerations include pancreatitis (discontinue if suspected), gallbladder disease, potential thyroid C-cell tumors (based on rodent studies), risk of hypoglycemia when used with insulin or sulfonylureas, and potential for acute kidney injury with severe dehydration

A couple of the most well-known are tirzepatide (Zepbound) and semaglutide (Wegovy)

Adequate hydration and consistent eating patterns, even when appetite is reduced, usually help

It's important to note that the FDA has determined there is no increased risk of suicidal ideation and behavior associated with these medications, which is a reassuring update for patients [e6ad]

B vitamins are essential for the body to function properly