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In addition, interactions with acid-suppressing agents (e.g., PPIs) can impair absorption of pH-sensitive oral agents like erlotinib, further complicating therapeutic management

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doi: 10.1590/S1807-59322010000500006

APAP toxicity, whether resulting from a single overdose or repeated supratherapeutic ingestion, progresses through four phases: preclinical toxic effects (phase one), hepatic injury (phase two), hepatic failure (phase three), and recovery (phase four)

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