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Finally, the dynamic crosstalk between microglia and other CNS cell types, including astrocytes, neurons, and endothelial cells, complicates the isolation of microglia-specific therapeutic effects

Abstract This study aimed to evaluate serum growth differentiation factor 15 (GDF15) as a potential supportive biomarker for fibromyalgia (FM) and investigate its association with disease severity

For example, PINK1 and Parkin loss of function impair mitophagy and cause accumulation of damaged mitochondria, leading to enhanced electron leakage and formation of superoxides 11,12,13

] Uribe PM, Kawas LH, Harding JW, Coffin AB

& Hultgren, S