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This carefully calibrated receptor selectivity profile contributes to the favorable side effect profile observed in clinical studies, where gastrointestinal adverse events were predominantly mild and occurred mainly during dose escalation phases

Effective biosimilar development pathway strategies and robust patient adherence improvement strategies are critical for market entry in cost-sensitive regions

For obesity, AACE and Obesity Society guidelines endorse using GLP-1 RAs when BMI criteria are met and lifestyle measures need augmentation, especially if there are weight-related comorbidities

Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease