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These non-incretin metabolic peptides frequently exert effects on peripheral tissues such as skeletal muscle, adipose tissue, liver, and vasculature, and often engage receptors distinct from those targeted by current therapies

Physical trauma, known as the Koebner phenomenon, can induce the appearance of vitiligo patches in areas of repeated friction, wounds, scars, and pre-existing lesions of contact eczema or psoriasis.76 Exposure to chemicals, such as phenolic derivatives, generates a melanotoxic effect in vitiligo by inducing oxidative stress and causing direct damage to melanocytes

Side Effect Management: Our providers monitor for gastrointestinal symptoms like nausea, reflux, or constipation, providing medical strategies to mitigate them before they become severe