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found that GLP-1RAs did not significantly reduce asthma exacerbations, whereas, SGLT-2 inhibitors (SGLT-2i) were associated with a reduced risk of asthma compared to both GLP-1RAs and DPP-4 inhibitors (DPP-4i) [101]

Tirzepatide is a dual-receptor agonist that rewires appetite signaling from the gut to the brain

In this aspect, this comprehensive literature review aims to provide a holistic approach by critically summarizing and scrutinizing the potential molecular processes and mechanisms governing drugs and chemical transfer and metabolism across the placental barrier, which may lead to fetotoxicity effects, as well as analyzing the currently available experimental methodologies used to assess xenobiotics placental transfer and metabolism

(PubMed) Shi H, Jing X, Wei X, et al

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