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These typically peak in the first 12 weeks after starting or increasing dose, then improve by weeks 34 as your body adapts

This difference explains why the trial will likely be terminated early, and a more objective background risk estimation needs to be performed (if available) compared to heterogeneous prevalence studies

But for users whose sexual dysfunction is significantly affecting quality of life and relationship satisfaction, it represents a targeted, evidence-based option worth discussing with a prescriber

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