Bridge, Glutamate cysteine ligase and the age-related decline in cellular glutathione: The therapeutic potential of -glutamylcysteine
Then, samples were diluted with a solution containing phosphate buffer (0.01 mol/L monobasic potassium phosphate/dibasic potassium phosphate, pH 6.85) containing sodium dithionite, and after 10 min at room temperature, absorbance was measured at 420 and 432 nm against a matched curve containing only buffer [21]
The role of glutathione in photosynthetic organisms: Emerging functions for glutaredoxins and glutathionylation
In April 2025 Pfizer was forced to discontinue a clinical trial with one of its experimental GLP-1 medicines to treat obesity due to potential drug induced liver injury found in one of the participants
4 Conclusion and outlook This article reviews the molecular mechanisms of ferroptosis-induced osteoporosis, summarizes the signaling pathways through which ferroptosis affects bone metabolism, and focuses on the three-dimensional regulatory network of iron metabolism disorder, lipid peroxidation and bone homeostasis imbalance
