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Atezolizumab is a PD-L1 inhibitor that is being studied in combination with cobimetinib and vemurafenib (types of targeted therapy)

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Oral B12 (50150 g daily) may be appropriate for dietary deficiency without neurological involvement, but intramuscular hydroxocobalamin injections remain first-line treatment in the UK for patients with nerve symptoms or malabsorption conditions

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The burden of mortality attributable to diabetes: realistic estimates for the year 2000

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