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We detected ACTL6A protein expression of 48 GC samples, those higher than the upper quartile are defined as high ACTL6A group, and those lower than the lower quartile are defined as low ACTL6A group

That's in addition to, as mentioned by Gambit, excess alcohol causing issues with the liver which is the primary bodily store of B12

however, it significantly elevates the incidence of aneuploidy in blastocysts ( 2 The impact of oxidative stress on oocyte development While advancements in assisted reproductive technology have addressed infertility issues in some younger women, they cannot fully compensate for the fertility decline observed in women of advanced reproductive age, particularly those over 40 years of age ( Figure 1 )