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If baseline ALT or AST levels exceed three times the upper limit of normal (ULN), evaluation for underlying causes is appropriate, though this need not necessarily delay semaglutide initiation if benefits are deemed to outweigh risks

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It may not have been dosed correctly." 'Losing 8 litres of fluid a day' on retatrutide Dr Holt, a gastroenterologist who focuses on the digestive system, including the stomach, intestines and liver, treated patients who had "become very unwell" after injecting high doses of retatrutide