Patients who were prescribed a GLP-1 were compared to those prescribed a different type of weight loss medication
Petersburg Institute of Bioregulation and Gerontology in Russia
[DOI] [PMC free article] [PubMed] [Google Scholar] 141.Inzucchi SE, Zinman B, Fitchett D, Wanner C, Ferrannini E, Schumacher M, Schmoor C, Ohneberg K, Johansen OE, George JT, Hantel S, Bluhmki E, Lachin JM
All participants gave informed consent and received an inconvenience allowance
Their platform (named CRIMSON-HD) validated mutations giving type I (ITGA2B p.G201S), type II (ITGA2B p.A777D and p.Q778P) and type III variant-type GT (Japanese KO variant: ITGA2B p.F191_S192insRT insertion) and functionally classified several variants whose significance was previously unresolved or controversial