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Gut-derived metabolites (e.g., SCFAs, indoles, secondary bile acids) and oxylipin signatures converge on metabolic pathways central to the CITleucineexercise synergy

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While preclinical data is promising, its important to recognize that neither peptide is FDA-approved for human therapeutic use, and most evidence is derived from animal or laboratory studies

It can result in premature ageing, pigmentation, and, in the worst cases, skin cancer

In case of fatty acid oxidation defects, acyl-carnitines accumulate in mitochondria and are transferred into the cytosol, and then into the blood