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Parenteral and intranasal cyanocobalamin, vitamin B12 are classified as pregnancy category C

Furthermore, they exhibited degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy

This aligns with user reports of stabilized improvements by month 4

Novel nasal niosomes loaded with lacosamide and coated with chitosan: a possible pathway to target the brain to control partial-onset seizures

Prophylactic B12 supplementation should be considered for specific high-risk groups