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The oxidative damage caused by mitochondrial ROS production has been identified as the molecular basis for several pathological changes, such as accelerated aging and cancer
doi: 10.1038/s41423-021-00757-x 29 Garcia-VarelaL.MosselP.AguiarP.Vasquez-MatiasD.van WaardeA.WillemsenA.et al
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Melatonin biosynthesis is enzymatically transformed, non-enzymatically or pseudo-enzymatically into numerous active metabolites such as AFMK (N1-acetyl-N2-formyl-5-methoxykynuramine), 5-MT (5-methoxytrayptamine), C3HMO (cyclic 3-hydroxymelatonin) and AMK N1-acetyl-5-methokynuramine (175)
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