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What To Know When Taking Semaglutide Tips for Managing Fatigue If you're experiencing fatigue while on semaglutide, these practical steps may help boost your energy levels: Prioritize hydration: Fatigue is often worsened by dehydration, especially if you're experiencing GI side effects like nausea or diarrhea

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The appetite regulation benefits of adequate sleep become particularly important when medication-driven appetite suppression is reduced during your transition period

Other studies found no strong link in clinical trials, but some users on social media are saying they experienced breakouts when first starting on GLP-1 medication

Novo Nordisk provides doctors and clinics with free samples of their medications to help their patients get started on treatment