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doi: 10.1111/dom.12885 Summary Keywords lipodystrophy, glucagon-like peptide-1, diabetes, seipin, liraglutide Citation Roumane A, Mcilroy GD, Sommer N, Han W, Heisler LK and Rochford JJ (2024) GLP-1 receptor agonist improves metabolic disease in a pre-clinical model of lipodystrophy
Red-flag symptoms to call your clinician about Severe, persistent abdominal pain, especially radiating to the back (pancreatitis evaluation) Right-upper-quadrant pain, fever, jaundice (gallbladder disease) Severe vomiting, inability to tolerate fluids, or severe constipation/bloating (possible ileus or marked delayed emptying) Black stools or blood in stool/vomit (urgent evaluation) Product labels and FDA communications specify stopping the drug and urgent workup for suspected pancreatitis or gallbladder complications
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Plus, since semaglutide lowers appetite and side effects include digestive issues like nausea, vomiting, and abdominal discomfort, it is not always easy to get the proper nutrients in the diet