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Synthetic mimics of seleno-GPxs, such as organoselenium compounds, are being developed to enhance antioxidant capacity in conditions where natural GPx is insufficient, like in selenium-deficient populations or chronic illnesses

But of the 13 consensus ratings of the companies in its portfolio, 11 assign the ETF a Buy or Moderate Buy rating, while just two assign it a Hold, and none rate it a Sell

Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis

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