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During treatment of the PDX model of osteosarcoma, since the individuality of the mice, the tumor volume of one mouse reached 1500 mm 3 by the end of the treatment, and this mouse was not euthanized in time to obtain reliable and intuitive experimental results

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Samples were then amplified and sequenced on a NextSeq 500 system (Illumina), where an average of 30 million reads were generated from each sample

( The thyroid is a small gland at the base of the neck below Adams apple .) Iodine deficiency can result in serious health conditions, including the following: Goiter (enlarged thyroid): As it tries to keep up with the demand for thyroid hormone, the thyroid becomes enlarged and nodules may develop

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