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There is increasing research and interest in combination therapies, such as pairing GLP-1 receptor agonists with other metabolic agents, to enhance efficacy as well as support patient adherence

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Many people call it CIU

Wherein the crystalline solid compound is preferably selected from: the optically pure compound of formula (II) in the present invention is selected from (+) -methyl-6-methoxy-2-naphthyl acetyl chloride, (+) -methyl-6-ethoxy-2-naphthyl acetyl chloride and their crystalline

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