It is not legally approved for human use outside of approved studies
MC1R is the primary melanocortin receptor governing skin pigmentation and expressed on melanocytes, keratinocytes, fibroblasts, and immune cells in the skin , whose activation by -MSH drives melanin synthesis, melanocyte dendritic extension, photoprotective eumelanin production, and anti-inflammatory signalling in response to ultraviolet radiation
Factors influencing dose conversion The following factors influence dose conversion: Individualized treatment: The conversion recommendations provide general guidance, but dosage adjustments may be necessary based on your bodys response
As of May 2025, the case remains pending in New Jersey state court
Using that approach, the current picture is fairly clear