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CJC-1295 with DAC (drug-affinity complex) includes a modification that binds the peptide to serum albumin, extending its half-life to roughly 5.8 to 8.1 days

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Figure 4: Change from Baseline (%) in Body Weight in Study 2 in Patients with Obesity or Overweight and Type 2 Diabetes Note: Displayed results are from the Intent-to-Treat Population

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Facet-mediated pain typically worsens with extension movements and prolonged standing