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However, this risk is significantly increased when it is used in combination with insulin or insulin secretagogues (e.g., sulfonylureas)

The level of insulin resistance was evaluated by the homeostasis model assessment of insulin resistance index (HOMA-IR), which was calculated with the following model: HOMA-IR = insulin [mIU/L] glucose [mmol/L]/22.5, and values exceeding 2.25 would denote insulin resistance [11]

EGCG may indirectly influence GLP-1 pathways or exert synergistic effects with other compounds to improve glucose metabolism and promote fat oxidation, contributing to overall metabolic well-being

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CE-2) or HFD (HFD-32) was given