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Weight loss edge: tirzepatide The clinical evidence is now definitive tirzepatide produces greater average weight loss than semaglutide across trials and real-world data

This reduces the concentrated volume at each site and may decrease reaction severity

If you are currently taking oral contraceptives, switch from an oral hormonal contraceptive to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation with Mounjaro

These medications should be recommenced once the patient is clinically well, euvolemic and tolerating an oral diet

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