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Among metal elements that perform essential biological functions, such as iron, zinc, and copper, copper demonstrates distinct advantages due to its unique chemical properties

ARBs and SGLT2 inhibitors could exert sympathoinhibitory effects in HF [70,71,72,73] and thus restore the diuretic and natriuretic effects of GLP-1

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Restoring normal rhythmicity through chromatin remodeling could provide benefits beyond what would be achieved by simply increasing overall biosynthetic capacity