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In clinical pharmacology trials, semaglutide did not affect the absorption of orally administered medications to any clinically relevant degree [see Clinical Pharmacology (12.3)]

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Cramping, particularly in the calves and feet at night, is a telltale sign of electrolyte deficiency

Monitor the injection site for reactions

Now, researchers at UC San Diego are exploring whether semaglutide, the active ingredient in those medications, could also help slow biological aging