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After receiving 28 days of treatment, different dose groups of ZSP601 showed significant improvements in metabolism, hepatic fat content, inflammation and fibrosis biomarker indices (262), supporting the evaluation of its long-term safety and efficacy in a larger sample size of MASH patients

Western blot analysis showed that the urothelium of mice pre-treated with PMF90 expressed small amounts of Cx43 and other inflammatory markers as compared to mice group receiving cyclophosphamide alone

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