Chronic Oxidative Stress (Depletes Glutathione Faster Than Its Made) Anything that increases free radical production depletes glutathione: Chronic inflammation (autoimmune diseases, obesity, metabolic syndrome) Environmental toxins (air pollution, pesticides, heavy metals) Alcohol consumption (glutathione is rapidly depleted in liver detoxification) Poor diet (high in processed foods, seed oils, sugar) Intense exercise (without adequate recovery) When oxidative stress exceeds your bodys capacity to recycle GSSG back to GSH, levels drop [4]
Biodistribution of 2 modified Ad5 adenovirus vectors (Adv) in mice, the enhanced infection AdpK7, and the fiber deleted Ad5.F: Ablation of both the fiber/CAR and integrin/penton interactions is necessary to block infection
Esta reaccin es posible debido a que el glutatin se encuentra en una proporcin relativamente alta en las clulas (de hasta 5 mM, en los hepatocitos)
Akiyama H, Zhao R, Nishida Y, Ostermann LB, Mak PY, Ayoub E, Piya S, Carter BZ, Andreeff M , Ishizawa J
Think of collagen as the "glue" that holds everything together