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Matsumoto, K., Funakoshi, H., Takahashi, H
As a result, pyridoxine deficiency can lead to relevant neuropsychiatric manifestations, such as reduced neurotransmitter synthesis, depression, epilepsy, premature aging of neurons, paresthesias, cerebrovascular diseases, cognitive impairment and carpal tunnel syndrome (58) In contrast, pyridoxine may have therapeutic potential for treating depression or aggressive behavior, since pyridoxine plays a crucial role in the tryptophan-serotonin pathway (61, 62)
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Previous studies have reported that decreased expression of GSTA4 is associated with positive outcomes in glioma models ( GSTA4 is the only one that has a gene promoter CpG island ( GSTA4 promoter methylation is associated with increased GSTA4 mRNA expression
A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory
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