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According to the National Institutes of Health, your body can store up to 2,000 times the amount of B12 you typically get in a day

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Drug Interactions: Patients treated with L-Dopa should not take high doses of pyridoxine (Vitamin B6) and thus Neuroton , as pyridoxine reduces the effects of L-Dopa

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Passive diffusion accounts for about 1% of total absorption, and this route of absorption is unaffected in patients with pernicious anemia ( There were studies in the 1950s and the1960s that showed that oral vitamin B12 could be absorbed by patients with pernicious anemia and could lead to resolution of the anemia (6)