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These include: Paraesthesia (pins and needles) in hands and feet Difficulty walking or balance problems Memory impairment and cognitive changes Mood disturbances, including depression and irritability Visual disturbances (rare, such as optic neuropathy) Gastrointestinal symptoms such as diarrhoea, constipation, or loss of appetite may also occur, particularly when deficiency results from malabsorption

These metabolites may have value as biomarkers for monitoring seizure activity and evaluating therapeutic efficacy

While two studies sourced their controls by community advertising [75, 86], most were sourced from hospitals, clinics or schools [71, 72, 77, 79, 83, 85, 88, 92, 93] and fourteen studies did not provide information on the source of their controls [48, 59, 60, 63, 6870, 73, 74, 76, 78, 81, 84]

If you're allergic to sulfa, you should avoid food and drinks containing sulfites such as dried fruits, wine, and processed foods