Gut microbiome analysis To further investigate whether GLP-1 treatment influences the intestinal microflora, we tested the microbial composition among four groups of mice (Figure 6)
-Rich in fiber: The FDA qualifies this as "high" or an "excellent source," and means it contains at least 20% or more of the Daily Value
However, excessive or systemic induction of ferroptosis may cause normal tissue toxicity and impair immune cell function, emphasizing the need for precise spatiotemporal control in therapeutic regimens
After 5 d of treatment, cells were harvested, washed with PBS, snap-frozen with liquid nitrogen, and stored at 80C
Thus, LDs function as dynamic lipid reserves, mobilizing stored FAs for cellular energy metabolism, and as cytoprotective structures that safeguard cells from lipotoxic stress [94, 95]