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New drugs that affect synaptic plasticity, social learning or neuroinflammation must be combined with psychological interventions to achieve complementary synergies that ultimately have a major impact on the long-term outcomes of individuals with autism

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Peptides often interfere with endotoxin detection due to their tendency to bind or mask endotoxins, which can lead to inaccurate low results

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Further structural optimization delivered a large number of macrocyclic disulfides and among them 23 (HA08) encompassing a 3-homotyrosine residue in a 13-membered ring system and exhibiting the lowest Ki value in the series (Ki = 3.3 nM)