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So I still find that using a phenotypic approach even with pharmacotherapy can be very advantageous for the patients because it really rounds out: how do I treat the patient in front of me, even though it's the same medication I use for the past five patients

2.2 Experimental design To establish individualized protocols for the acute exercise trials, participants visited the study center on a separate day before study onset, performing a cardiopulmonary exercise test on a bicycle ergometer

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The absence of human adverse-event data is itself a safety data gap, not evidence of safety