So we are probably less exposed than most of the industry, I would say. Look at the way companies are starting to have to defend themselves and explain their business
The derivatization protocol for the quantification of TMA was an adaptation of the protocol described by Samples for TMAO levels quantification were prepared as follows: an amount of 25 L of each sample was collected, and 3 L of D9-TMAO (5 M concentration) and 122 L of a cold acetonitrile:methanol mixture (50:50, v/v) were added for protein precipitation
Menstruating women, vegetarians, vegans, individuals with pre-existing anaemia, those with malabsorption disorders, and patients experiencing persistent gastrointestinal side effects are at higher risk of iron deficiency during Wegovy treatment
Notably, the metabolic benefits of dual GLP-1R/GcgR agonists have also been documented in obese non-human primates, where chronic administration of a lower dose of a GLP-1R/GcgR co-agonist vs a GLP-1R mono-agonist reduced body weight and improved glucose tolerance to a greater degree [77]
However, many of the strongest claims come from animal studies, small-scale research, anecdotal reports, or non-medical online sources
