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Whole-exome sequencing captures all coding regions, including both highly penetrant variants as well as incomplete penetrance variants that require to be classified following ACMG pathogenicity criteria

Results Glutathione Metabolism Is Altered in Murine Lung during Influenza Infection To investigate metabolic changes in the lung during influenza infection, we performed metabolomic analyses (Figure 1A) on both influenza-infected and control mice over multiple time points

By addressing both the biological rationale and methodological limitations of existing studies, this review provides insight that could be used as a reference to inform clinical decision-making and support the development of robust, evidence-based guidelines for tinnitus management